The combined use of scaffolds, cells, and bioactive molecules such as peptides is considered the best approach to achieve tissue regeneration. Regeneration depends on the natural capacity of the body and the use of biomaterials and bioactive molecules that can module the processes to replace lost or damaged tissues and restore function. Regenerative therapy in oral tissues has gained relevance since tissue loss due to congenital or acquired diseases as well as trauma is a major health problem worldwide. 4Facultad de Odontología, Universidad Autónoma de Sinaloa, Culiacán, Mexico.3Facultad de Odontología, Universidad Autónoma de Chihuahua, Chihuahua, Mexico. 2Facultad de Odontología, Universidad Nacional Autónoma de México, CDMX, Mexico.1Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán, Mexico.Mercedes Bermúdez 1* †, Lía Hoz 2 †, Gonzalo Montoya 2 †, Mikado Nidome 2, Adriana Pérez-Soria 2 †, Enrique Romo 2 †, Uriel Soto-Barreras 3 †, Julio Garnica-Palazuelos 4, Maribel Aguilar-Medina 1, Rosalío Ramos-Payán 1 and Carlos Villegas-Mercado 4* †
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